CIRCULATING TUMOR DNA TESTING SUPPORTS RAPID THERAPEUTIC DECISION-MAKING IN METASTATIC MELANOMA: A CASE REPORT

Circulating Tumor DNA Testing Supports Rapid Therapeutic Decision-Making in Metastatic Melanoma: A Case Report

Treatment of metastatic melanoma includes the option of targeted therapy in patients with driver BRAF mutations.BRAF-MEK inhibitor drugs improve survival in the approximately 50% of patients with melanoma that harbor BRAF mutations.As BRAF mutation detection in tissue often takes days to weeks, it is not always possible or timely to obtain BRAF sta

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Emission Characteristics for a Homogeneous Charged Compression Ignition Diesel Engine with Exhaust Gas Recirculation Using Split Injection Methodology

Due to the serious issues caused by air pollution and global warming, emission regulations are becoming stricter.New technologies that reduce NOx and PM emissions are needed.To cope with these Gas Range Cooker social exhaust gas regulation demands, many advanced countries are striving to develop eco-friendly vehicles in order to respond to stricter

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A systematic review and individual patient data meta-analysis of prognostic factors for foot ulceration in people with diabetes: the international research collaboration for the prediction of diabetic foot ulcerations (PODUS)

Background: Annual foot risk assessment of people with diabetes is recommended in national and international clinical guidelines.At present, these are consensus based and use only a proportion of the available evidence.Objectives: We undertook a systematic review of individual patient data (IPD) to identify the most highly prognostic factors for fo

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